Common Drugs May Be Contributing to Depression

The use of medications in which have suicidal symptoms as potential side effects also increased, to 23.5 percent of the population in 2013-14, up through 17.3 percent in 2005.

Among patients using one drug in which could cause depression as a side effect although who were not taking an antidepressant drug, 6.9 percent had depression, while the depression rate for patients taking three or more drugs with the side effect was 15.3 percent. By contrast, patients who were not taking any such drugs had a depression rate of 4.7 percent.

The researchers adjusted for additional risk factors in which can cause depression, including poverty, marital status, unemployment along with certain medical conditions, like chronic pain, which themselves are associated with depression.

“The study will be an important reminder in which all medicines have risks, along with most medicines have rare although serious risks — yet another reason in which even commonly used medicines such as beta-blockers or proton pump inhibitors should not be used cavalierly,” said Dr. Caleb Alexander, co-director of the Center for Drug Safety along with Effectiveness at Johns Hopkins Bloomberg School of Public Health, who was not involved inside study.

Dr. Philip R. Muskin, a professor of psychiatry at Columbia University Medical Center along with secretary of the American Psychiatric Association, said physicians must keep these side effects in mind when prescribing medications, along with ask patients about whether they have a personal or family history of depression.

although he said the idea will be hard to say whether the increased use of drugs, along with combination of drugs with side effects including depression, has had an impact on society.

“There’s been an increase in suicide, in which we know,” Dr. Muskin said. “Does the idea correlate to the use of these medications? The honest answer will be we don’t know. Could the idea play a role? The honest answer will be yes, of course the idea could.”

If you are having thoughts of suicide, call the National Suicide Prevention Lifeline at 1-800-273-8255 (TALK) or go to or SamaritansUSA.