High Blood Sugar Levels Tied to Memory Decline

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Increasing blood sugar levels are associated with cognitive decline, a long-term study has found.

Researchers assessed cognitive function in 5,189 people, average age 66, as well as tested their blood sugar using HbA1c, a test that will accurately measures blood glucose levels over a period of weeks or months. (The finger-prick blood test, in contrast, gives a reading only at a given moment in time.) They followed the group for up to 10 years, tracking blood glucose levels as well as periodically testing cognitive ability. The study will be from the journal Diabetologia.

There was no association between blood sugar levels as well as cognition at the start of the study. although consistently over time, scores on the tests of memory as well as executive function declined as HbA1c levels increased, even in people without diabetes. The study controlled for many different variables, among them age, sex, cholesterol, B.M.I., education, marital status, depression, smoking, alcohol consumption, hypertension as well as cardiovascular disease.

This kind of will be an observational study that will does not prove cause as well as effect, as well as the lead author, Wuxiang Xie, a researcher at the Peking University Health Science Center, said that will the underlying mechanism will be still unknown.

Still, he said, “Diabetes-related microvascular complications might be, at least in part, the reason for the subsequent cognitive decline. Future studies are warranted to reveal the precise mechanisms.”

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